Description

-Ether-Peg5-Amine is a specialized bifunctional polyethylene glycol (PEG) derivative featuring an ether linkage and a terminal primary amine group. This molecular architecture is critical for creating stable, hydrophilic linkers in bioconjugation and advanced material synthesis. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, reproducible spacer molecules. The compound's unique structure facilitates the coupling of active molecules while maintaining solubility and reducing immunogenicity.

Application

• Bioconjugation Linker: Serves as a hydrophilic spacer for attaching drugs, proteins, or fluorescent dyes to nanoparticles, antibodies, or other targeting moieties.
• Polymer Modification: Used as a functional monomer or chain extender to introduce amine functionality into PEG-based copolymers, hydrogels, and dendrimers.
• Surface Functionalization: Employed to amine-functionalize surfaces (e.g., gold, silica, polymers) for subsequent immobilization of biomolecules in diagnostic assays and biosensors.
• Peptide & Protein PEGylation: Acts as a reagent for site-specific or random PEGylation to enhance the stability, solubility, and circulation half-life of therapeutic peptides and proteins.
• Crosslinking Agent: Utilized in the formation of crosslinked networks for hydrogels and controlled-release drug delivery systems due to its reactive amine group.
• Lipid-Nanoparticle (LNP) Formulation: A key component in the synthesis of ionizable lipids or PEG-lipids for mRNA and siRNA delivery systems.

Basic Information

Product Name	-Ether-Peg5-Amine
CAS No.	2341841-01-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Amino-PEG5-alcohol ether; 2,5,8,11,14-Pentaoxaheptadecan-17-amine; 17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-ol; Heterobifunctional PEG5 Amine; Amine-PEG5-OH; Hydroxy-PEG5-amine; mPEG5-NH2; PEG5 spacer amine
EINECS	Contact for details

Quality Control

Our -Ether-Peg5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and cGMP manufacturing. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Under inert atmosphere (argon or nitrogen) is recommended for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Assay (Titration)	95.0 - 105.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.