Description

3-Fluoromethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride is a high-purity, protected piperazine derivative that serves as a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and other bioactive compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Development: Used in the construction of complex molecular scaffolds for potential Active Pharmaceutical Ingredients.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Serves as a constrained, fluorinated building block for creating peptide analogs and mimetics.
• Agrochemical Research: Employed in the development of new crop protection agents and herbicides.
• Chemical Biology Probes: Useful for creating labeled or modified compounds for studying biological pathways.

Basic Information

Product Name	3-Fluoromethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride
CAS No.	2331259-80-2
Molecular Formula	C11H22ClFN2O2
Molecular Weight	268.76 g/mol
Synonyms	1-Boc-3-(fluoromethyl)piperazine hydrochloride; tert-Butyl 3-(fluoromethyl)piperazine-1-carboxylate hydrochloride; 3-(Fluoromethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester hydrochloride; 1-N-Boc-3-fluoromethylpiperazine HCl; Boc-3-fluoromethylpiperazine hydrochloride; 3-Fluoromethyl-1-Boc-piperazine hydrochloride; N-Boc-3-(fluoromethyl)piperazine HCl
EINECS	Contact for details

Quality Control

Our 3-Fluoromethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.