Description

(3R,4R)-3-Hydroxy-4-Methyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester CAS NO 2326413-71-0 is a high-purity, chiral piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its defined stereochemistry and protected amine functionality, which are essential for constructing complex molecular architectures with high enantiomeric purity. It is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and other specialized organic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the research and production of advanced, stereospecific pesticides and herbicides.
• Catalyst & Ligand Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereocenters.

Basic Information

Product Name	(3R,4R)-3-Hydroxy-4-Methyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	2326413-71-0
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	tert-Butyl (3R,4R)-3-hydroxy-4-methylpiperidine-1-carboxylate; 1-Boc-3R-hydroxy-4R-methylpiperidine; (3R,4R)-1-N-Boc-3-hydroxy-4-methylpiperidine; (3R,4R)-3-Hydroxy-4-methyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl (3R,4R)-3-hydroxy-4-methyl-1-piperidinecarboxylate; (3R,4R)-3-Hydroxy-N-Boc-4-methylpiperidine; BOC-(3R,4R)-3-Hydroxy-4-methylpiperidine
EINECS	Contact for details

Quality Control

Every batch of (3R,4R)-3-Hydroxy-4-Methyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with industry standards for advanced intermediates. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.