Description

1-Benzyl-4-(Oxetan-3-Yl)Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a unique piperazine-oxetane hybrid scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with improved metabolic stability and pharmacokinetic profiles. Pharmaceutical R&D and fine chemical synthesis companies need it for developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the oxetane moiety for enhancing drug-like properties.
• Proteolysis Targeting Chimera (PROTAC) Linker: Serves as a potential component in the design of bifunctional molecules for targeted protein degradation.
• Kinase Inhibitor Synthesis: Employed in the construction of novel kinase inhibitor scaffolds for oncology research.
• CNS Drug Discovery: Utilized in synthesizing compounds targeting neurological disorders due to the favorable properties of the piperazine core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	1-Benzyl-4-(Oxetan-3-Yl)Piperazine
CAS No.	2322073-91-4
Molecular Formula	C14H20N2O
Molecular Weight	232.32 g/mol
Synonyms	1-Benzyl-4-(oxetan-3-yl)piperazine; 3-(4-Benzylpiperazin-1-yl)oxetane; Oxetan-3-yl-4-benzylpiperazine; 4-Benzyl-1-(oxetan-3-yl)piperazine; BOP; 1-(Oxetan-3-yl)-4-benzylpiperazine; Benzyl-oxetanyl-piperazine; N-Benzyl-N'-(oxetan-3-yl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-(Oxetan-3-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.