Description

2-(4-((Benzyloxy)Carbonyl)Piperazin-1-Yl)Acetic Acid Hydrochloride is a high-purity, non-natural amino acid derivative and a key pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex molecules, particularly in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, where it is used to construct novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce functionalized piperazine moieties, modifying peptide properties.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology: Employed in the development of chemical probes and tools to study biological systems and enzyme functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for clients.
• Library Synthesis: Used to generate diverse compound libraries for high-throughput screening in early-stage drug discovery.

Basic Information

Product Name	2-(4-((Benzyloxy)Carbonyl)Piperazin-1-Yl)Acetic Acid Hydrochloride
CAS No.	2306272-72-8
Molecular Formula	C14H19ClN2O4
Molecular Weight	314.77 g/mol
Synonyms	1-CBZ-Piperazine-1-acetic acid hydrochloride; N-Carbobenzyloxy-1-piperazineacetic acid hydrochloride; 1-[(Benzyloxy)carbonyl]piperazine-4-acetic acid hydrochloride; 2-[4-[(Benzyloxy)carbonyl]piperazin-1-yl]acetic acid hydrochloride; (1-CBZ-Piperazin-4-yl)acetic acid HCl; Z-Pip-OH.HCl; Piperazine-1-acetic acid, 4-[(phenylmethoxy)carbonyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-(4-((Benzyloxy)Carbonyl)Piperazin-1-Yl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.