Description

Benzyl (R)-2-(Cyanomethyl)Piperazine-1-Carboxylate is a high-purity chiral piperazine derivative, serving as a critical building block in modern organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis.
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs and constrained scaffolds for medicinal chemistry.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a defined stereochemical center.

Basic Information

Product Name	Benzyl (R)-2-(Cyanomethyl)Piperazine-1-Carboxylate
CAS No.	2306255-32-1
Molecular Formula	C14H17N3O2
Molecular Weight	259.31 g/mol
Synonyms	(R)-1-Benzyloxycarbonyl-2-(cyanomethyl)piperazine; (R)-1-Cbz-2-(cyanomethyl)piperazine; Benzyl (R)-2-(cyanomethyl)piperazine-1-carboxylate; (R)-Cbz-2-(Cyanomethyl)piperazine; 1-[(Benzyloxy)carbonyl]-2-[(cyanomethyl)methyl]-(2R)-piperazine; (R)-N-Cbz-2-(Cyanomethyl)piperazine; (R)-1-(Benzyloxycarbonyl)-2-(cyanomethyl)piperazine; Piperazine-1-carboxylic acid, 2-(cyanomethyl)-, benzyl ester, (2R)-
EINECS	Contact for details

Quality Control

Our Benzyl (R)-2-(Cyanomethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.