Description

tert-Butyl (R)-3-(Cyanomethyl)Piperazine-1-Carboxylate is a high-purity, chiral piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its role as a protected intermediate, enabling the controlled introduction of the (R)-3-(cyanomethyl)piperazine moiety into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active molecules for crop protection and pest management solutions.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial laboratories for exploring new synthetic pathways and novel compound libraries.
• Peptidomimetics & Bioactive Molecule Design: The piperazine core and cyanomethyl side chain are valuable for constructing peptide analogs and other bioactive compounds with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the scalable production of client-specific target molecules.

Basic Information

Product Name	tert-Butyl (R)-3-(Cyanomethyl)Piperazine-1-Carboxylate
CAS No.	2306248-13-3
Molecular Formula	C11H19N3O2
Molecular Weight	225.29 g/mol
Synonyms	1-Boc-(R)-3-(Cyanomethyl)piperazine; (R)-1-(tert-Butoxycarbonyl)-3-(cyanomethyl)piperazine; tert-Butyl (R)-(-)-3-(Cyanomethyl)-1-piperazinecarboxylate; (R)-3-(Cyanomethyl)-1-Boc-piperazine; 1-N-Boc-3(R)-(cyanomethyl)piperazine; (R)-1-Boc-3-(cyanomethyl)piperazine; Boc-(R)-3-(Cyanomethyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl (R)-3-(Cyanomethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97%), and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.