Description

2-Pyrazinecarboxaldehyde, 5-Bromo-3-Methoxy- CAS NO 2288709-85-1 is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile electrophilic intermediate, enabling the introduction of both bromo and aldehyde functionalities into complex molecular architectures. Pharmaceutical and agrochemical researchers need it for the development of novel active ingredients, particularly in medicinal chemistry for hit-to-lead optimization.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and antiviral agents.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Enables the creation of molecular probes for studying enzyme function and biological pathways.
• Advanced Material Development: Serves as a monomer or functionalizing agent for conductive polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	2-Pyrazinecarboxaldehyde, 5-Bromo-3-Methoxy-
CAS No.	2288709-85-1
Molecular Formula	C7H5BrN2O2
Molecular Weight	229.03 g/mol
Synonyms	5-Bromo-3-methoxypyrazine-2-carbaldehyde; 5-Bromo-3-methoxy-2-pyrazinecarboxaldehyde; 3-Methoxy-5-bromopyrazine-2-carboxaldehyde; 2-Pyrazinecarboxaldehyde, 5-bromo-3-methoxy-; 5-Bromo-3-methoxypyrazinecarbaldehyde; (5-Bromo-3-methoxypyrazin-2-yl)methanol (oxidized form); BRM
EINECS	Contact for details

Quality Control

Our 2-Pyrazinecarboxaldehyde, 5-Bromo-3-Methoxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider sealing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.