Description

m-Peg11-Acid is a monodisperse polyethylene glycol (PEG) derivative featuring a carboxylic acid functional group at one terminus and a methoxy group at the other. This bifunctional linker is engineered to provide a precisely defined, hydrophilic spacer arm for bioconjugation and surface modification applications. Its consistent chain length ensures reproducible performance in creating stable, water-soluble conjugates. This compound is essential for researchers and manufacturers in the pharmaceutical, diagnostics, and advanced materials sectors who require high-purity, well-characterized PEGylation reagents.

Application

• Bioconjugation Linker: Used to covalently attach peptides, proteins, or antibodies to surfaces, nanoparticles, or other biomolecules, improving solubility and stability.
• PEGylation Reagent: Serves as a critical intermediate in the synthesis of PEGylated drug conjugates, helping to prolong circulation time and reduce immunogenicity.
• Surface Functionalization: Modifies the surface properties of materials (e.g., quantum dots, magnetic beads, biosensors) to introduce carboxylic acid groups for further coupling chemistry.
• Hydrogel Synthesis: Acts as a cross-linking agent or functional monomer in the creation of biocompatible hydrogels for drug delivery and tissue engineering.
• Diagnostic Assay Development: Utilized in the preparation of enzyme-linked immunosorbent assay (ELISA) components and other diagnostic reagents.
• Polymer Chemistry Intermediate: A key building block for synthesizing more complex block copolymers and functionalized polymers with tailored properties.

Basic Information

Product Name	m-Peg11-Acid
CAS No.	2280998-74-3
Molecular Formula	C26H52O14
Molecular Weight	588.68 g/mol
Synonyms	mPEG11-COOH; Methoxy-PEG11-acid; α-Methoxy-ω-carboxy undeca(ethylene glycol); 2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-oic acid, 34-methoxy-; Monomethoxy undecaethylene glycol carboxylic acid; CH3O-(CH2CH2O)11-CH2COOH; PEG 500 acid, monomethyl ether; m-PEG11-AA
EINECS	Contact for details

Quality Control

Every batch of m-Peg11-Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive life science applications. Our quality control protocol includes HPLC for purity and assay, NMR for structural confirmation, and mass spectrometry for molecular weight verification. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
PEG Content (by NMR)	≥ 98.0%
Acid Value	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.