Description

Loxoprofen CAS NO 2274853-20-0 is a potent non-steroidal anti-inflammatory drug (NSAID) belonging to the propionic acid derivative class. This active pharmaceutical ingredient (API) is valued for its effective analgesic and anti-inflammatory properties, making it a critical component in the formulation of pain management medications. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of prescription and over-the-counter drugs targeting conditions such as rheumatoid arthritis, osteoarthritis, lumbago, and post-operative pain.

Application

• Pharmaceutical API: Primary use as the active ingredient in solid oral dosage forms (tablets, capsules) for pain and inflammation relief.
• Analgesic Formulations: Manufacturing of prescription and OTC medications for musculoskeletal pain, dental pain, and post-surgical pain management.
• Anti-inflammatory Drugs: Development of treatments for chronic inflammatory conditions like rheumatoid arthritis and osteoarthritis.
• Topical Preparations: Potential use in gels, creams, or patches for localized analgesic and anti-inflammatory effects (subject to formulation development).
• Clinical Research: Serving as a reference standard or investigational compound in pharmacological and pharmacokinetic studies.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of branded loxoprofen medications.

Basic Information

Product Name	Loxoprofen
CAS No.	2274853-20-0
Molecular Formula	C15H18O3
Molecular Weight	246.30 g/mol
Synonyms	Loxoprofen Sodium; (±)-2-[4-(2-Oxocyclopentylmethyl)phenyl]propionic Acid; Loxonin (Brand Name); CS-600; (RS)-2-[4-(2-Oxocyclopentylmethyl)phenyl]propanoic Acid; DL-Loxoprofen; Loxoprofen (Free Acid)
EINECS	Contact for details

Quality Control

Our Loxoprofen is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, related substances, residual solvents, and identification. Our quality commitment aligns with ICH guidelines and relevant pharmacopeial standards to ensure consistency and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Individual Unknown Impurity	≤ 0.10%
Residual Solvents (GC)	Meets ICH Q3C limits
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.