Description

2H-3-Benzazepin-2-One, 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]Octa-1,3,5-Trien-7-Yl]Methyl]Methylamino]Propyl]-1,3,4,5-Tetrahydro-5-Hydroxy-7,8-Dimethoxy- is a complex, high-purity organic compound belonging to the benzazepinone class, featuring a unique bicyclic structure. This compound is of significant interest for advanced research and development, particularly in the pharmaceutical sector, due to its sophisticated molecular architecture which is often associated with targeted biological activity. It serves as a critical pharmaceutical intermediate or reference standard for scientists and R&D teams engaged in the synthesis of novel therapeutic agents. The product is supplied with a focus on batch-to-batch consistency and analytical traceability to support rigorous development workflows.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Process Chemistry Development: Serves as a critical material for scaling up synthetic routes from laboratory to pilot plant scale.
• Biochemical Research: May be utilized as a tool compound in pharmacological assays to investigate specific receptor interactions or enzyme inhibition.
• Custom Synthesis Starting Material: Provides a sophisticated core structure for contract research organizations (CROs) and custom synthesis houses.

Basic Information

Product Name	2H-3-Benzazepin-2-One, 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]Octa-1,3,5-Trien-7-Yl]Methyl]Methylamino]Propyl]-1,3,4,5-Tetrahydro-5-Hydroxy-7,8-Dimethoxy-
CAS No.	2253977-80-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-5-hydroxy-7,8-dimethoxy-2H-3-benzazepin-2-one; (7S)-7-[[[3-[5-Hydroxy-2-oxo-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-3-yl]propyl]methylamino]methyl]-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene; CAS 2253977-80-7; Benzazepinone derivative; Advanced pharmaceutical intermediate 2253977-80-7.
EINECS	Contact for details

Quality Control

Our 2H-3-Benzazepin-2-One derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical R&D and reference materials. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the certificate of analysis. The product is light-sensitive (store away from light). Keep the container in a dry, well-ventilated area. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.