Description

tert-Butyl ((3S,4R)-3-Methoxypiperidin-4-Yl)Carbamate Hemioxalate is a high-purity chiral piperidine derivative and a key pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical manufacturers in the development and production of novel therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug molecules, particularly for central nervous system (CNS) and oncology targets.
• Chiral Synthesis: Used in asymmetric synthesis to introduce the (3S,4R)-3-methoxypiperidin-4-yl moiety with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for GMP (Good Manufacturing Practice) production.
• Reference Standard: Used as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	tert-Butyl ((3S,4R)-3-Methoxypiperidin-4-Yl)Carbamate Hemioxalate
CAS No.	2253105-08-5
Molecular Formula	C12H24N2O4 • 0.5C2H2O4
Molecular Weight	Contact for details
Synonyms	Boc-3-Methoxy-4-aminopiperidine Hemioxalate; (3S,4R)-1-Boc-3-Methoxy-4-aminopiperidine Hemioxalate; tert-Butyl N-[(3S,4R)-3-methoxypiperidin-4-yl]carbamate hemioxalate; (3S,4R)-4-[(tert-Butoxycarbonyl)amino]-3-methoxypiperidine hemioxalate; (3S,4R)-3-Methoxy-4-((tert-butoxycarbonyl)amino)piperidine hemioxalate; (3S,4R)-Boc-3-Methoxy-4-Aminopiperidine Hemioxalate Salt; (3S,4R)-1-Boc-3-Methoxy-4-Aminopiperidine Oxalic Acid Salt
EINECS	Contact for details

Quality Control

Our tert-Butyl ((3S,4R)-3-Methoxypiperidin-4-Yl)Carbamate Hemioxalate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and development. All products undergo rigorous analytical testing, including chiral purity verification by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.