Description

2-(Piperidin-3-Yl)Pyrazine Dihydrochloride is a high-purity, heterocyclic organic compound primarily utilized as a sophisticated building block in pharmaceutical research and development. Its unique fused piperidine-pyrazine structure makes it a valuable intermediate for synthesizing novel active pharmaceutical ingredients (APIs) and other biologically active molecules. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Chemical Biology Probes: Serves as a core scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Agrochemical Development: An intermediate in the research and synthesis of new crop protection agents and pesticides.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic chemistry and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	2-(Piperidin-3-Yl)Pyrazine Dihydrochloride
CAS No.	2244088-30-8
Molecular Formula	C9H14Cl2N4
Molecular Weight	249.14 g/mol
Synonyms	2-(3-Piperidinyl)pyrazine dihydrochloride; 2-(Piperidin-3-yl)pyrazine hydrochloride (1:2); Pyrazine, 2-(3-piperidinyl)-, dihydrochloride; 3-(Pyrazin-2-yl)piperidine dihydrochloride; 2-(3-Piperidyl)pyrazine dihydrochloride; 2244088-30-8; 2-Piperidin-3-ylpyrazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-3-Yl)Pyrazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications. We support development from milligram to kilogram scale with consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.