Description

tert-Butyl 4-(3-Cyano-4-(Methoxycarbonyl)Phenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with cyano and methoxycarbonyl functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its reactive cyano and ester groups.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for the production of Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	tert-Butyl 4-(3-Cyano-4-(Methoxycarbonyl)Phenyl)Piperazine-1-Carboxylate
CAS No.	2242744-14-3
Molecular Formula	C18H23N3O4
Molecular Weight	345.40 g/mol
Synonyms	1-Boc-4-(3-Cyano-4-(Methoxycarbonyl)Phenyl)Piperazine; tert-Butyl 4-(3-Cyano-4-(Methoxycarbonyl)phenyl)piperazine-1-carboxylate; 4-(3-Cyano-4-(methoxycarbonyl)phenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-[3-cyano-4-(methoxycarbonyl)phenyl]-1-piperazinecarboxylate; Methyl 2-cyano-4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzoate; CAS 2242744-14-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Cyano-4-(Methoxycarbonyl)Phenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for pharmaceutical research. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.