Description

tert-Butyl 4-[trans-2-Aminocyclohexyl]Piperazine-1-Carboxylate CAS NO 2227199-32-6 is a high-purity, advanced pharmaceutical intermediate featuring a unique piperazine-cyclohexylamine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel drug candidates. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutics, particularly in areas like central nervous system (CNS) agents and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening against biological targets.
• CNS Drug Development: The structural motif is relevant for developing potential therapeutics for neurological and psychiatric disorders.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Process Chemistry: Used in route scouting and scale-up studies for the commercial manufacturing of complex drug molecules.

Basic Information

Product Name	tert-Butyl 4-[trans-2-Aminocyclohexyl]Piperazine-1-Carboxylate
CAS No.	2227199-32-6
Molecular Formula	C15H29N3O2
Molecular Weight	283.42 g/mol
Synonyms	1-Boc-4-(trans-2-aminocyclohexyl)piperazine; tert-Butyl 4-[(1R,2R)-2-aminocyclohexyl]piperazine-1-carboxylate; 4-(trans-2-Aminocyclohexyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(trans-2-aminocyclohexyl)piperazine; trans-N-Boc-4-(2-aminocyclohexyl)piperazine; Boc-trans-2-ACPP; (trans)-1-Boc-4-(2-aminocyclohexyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[trans-2-Aminocyhexyl]Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.