Description

2,6-Piperidinedione, 3-[1,3-Dihydro-1-Oxo-5-(1-Piperazinyl)-2H-Isoindol-2-Yl]- is a high-purity, complex heterocyclic compound featuring a piperidinedione core fused with an isoindole moiety and a piperazine substituent. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate or research chemical for the development of novel active ingredients. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential therapeutic agents, particularly those targeting neurological or oncological pathways.
• Drug Discovery Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Potential tool compound for probing biological systems and enzyme interactions due to its unique heterocyclic structure.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex, specialty molecules in custom synthesis projects.

Basic Information

Product Name	2,6-Piperidinedione, 3-[1,3-Dihydro-1-Oxo-5-(1-Piperazinyl)-2H-Isoindol-2-Yl]-
CAS No.	2222120-30-9
Molecular Formula	C16H18N4O3
Molecular Weight	314.34 g/mol
Synonyms	3-[1,3-Dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-2,6-piperidinedione; 5-(Piperazin-1-yl)isoindoline-1,3-dione derivative; Related to Pomalidomide analogs; Isoindole-1,3-dione piperazine derivative; Heterocyclic piperazinyl isoindoledione
EINECS	Contact for details

Quality Control

Our 2,6-Piperidinedione derivative is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and results is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.