Description

1-(2-Fluoro-4-Methylbenzyl)-Piperazine Dihydrochloride is a high-purity, fluorinated piperazine derivative supplied as a stable dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is essential for medicinal chemistry research and process development in the pharmaceutical and biotechnology sectors, particularly for synthesizing compounds targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug candidates.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization programs to explore structure-activity relationships (SAR) and improve drug-like properties.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the development and optimization of scalable synthetic routes under GMP conditions.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and receptor binding studies.
• Custom Synthesis: Basis for the custom manufacturing of more complex, fluorinated specialty chemicals for various industrial applications.

Basic Information

Item	Detail
Product Name	1-(2-Fluoro-4-Methylbenzyl)-Piperazine Dihydrochloride
CAS No.	2208779-90-0
Molecular Formula	C12H18Cl2FN2
Molecular Weight	277.19 g/mol
Synonyms	1-[(2-Fluoro-4-methylphenyl)methyl]piperazine dihydrochloride; 2-Fluoro-4-methylbenzylpiperazine dihydrochloride; 1-(2-Fluoro-4-methylbenzyl)piperazine hydrochloride (1:2); (2-Fluoro-4-methylbenzyl)piperazine dihydrochloride; Piperazine, 1-[(2-fluoro-4-methylphenyl)methyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-4-Methylbenzyl)-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all specified parameters to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.