Description

6,7-Dihydropyrrolo[3,4-B]Pyrazin-5-One CAS NO 2203486-14-8 is a high-purity heterocyclic organic compound belonging to the fused pyrrolopyrazinone class, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and targeted therapy research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted small molecules.
• Oncology Research: Used in the discovery and development of novel anti-cancer agents due to its privileged scaffold commonly found in bioactive molecules.
• Medicinal Chemistry: Serves as a versatile core structure for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical assays and diagnostic tool development, leveraging its reactive sites.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex nitrogen-containing heterocycles for various high-value applications.

Basic Information

Product Name	6,7-Dihydropyrrolo[3,4-B]Pyrazin-5-One
CAS No.	2203486-14-8
Molecular Formula	C7H5N3O
Molecular Weight	147.14 g/mol
Synonyms	6,7-Dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one; 5H-Pyrrolo[3,4-b]pyrazin-5-one, 6,7-dihydro-; Pyrrolo[3,4-b]pyrazin-5(7H)-one; Fused pyrrolopyrazinone scaffold; Pharma Intermediate 2203486-14-8
EINECS	Contact for details

Quality Control

Our 6,7-Dihydropyrrolo[3,4-B]Pyrazin-5-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.