Description

Sodium 7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-3-carboxylate is a high-purity, protected heterocyclic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of complex molecules, particularly in the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of sophisticated drug candidates. The CAS number for this compound is 2177266-05-4.

Application

This advanced chemical intermediate is designed for specialized applications in organic synthesis, particularly within the life sciences sector.

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a defined intermediate for the development and optimization of robust, scalable manufacturing routes for APIs.
• Peptidomimetic & Heterocyclic Chemistry: The imidazopyrazine core is valuable for constructing peptidomimetics and other bioactive heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Item	Details
Product Name	Sodium 7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-3-carboxylate
CAS No.	2177266-05-4
Molecular Formula	C12H16N3NaO4
Molecular Weight	289.26 g/mol
Synonyms	7-(Boc)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-3-carboxylic acid sodium salt; Sodium 7-Boc-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-3-carboxylate; Boc-THIP-Carboxylate Sodium Salt; 1,2,3,4-Tetrahydroimidazo[1,5-a]pyrazine-7-carboxylic acid, 3-(1,1-dimethylethyl) ester, sodium salt (1:1); Imidazo[1,5-a]pyrazine-3-carboxylic acid, 5,6,7,8-tetrahydro-7-[(1,1-dimethylethoxy)carbonyl]-, sodium salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing batch-specific data. Our quality management system is designed to support cGMP (Current Good Manufacturing Practice) requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.