Description

(8Ar)-8A-Methyl-Octahydropyrrolo[1,2-A]Pyrazine Dihydrochloride is a high-purity, specialized organic salt used as a critical building block in advanced chemical synthesis. This compound matters because it provides a structurally defined, nitrogen-rich bicyclic framework essential for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities. CAS number is provided in the table below.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its unique heterocyclic structure for biological activity.
• Ligand Synthesis: Acts as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Chemistry: Provides a constrained scaffold for designing peptide analogs with enhanced stability and bioavailability.
• Academic & Process Chemistry: Employed in research laboratories for methodological studies and as a reference standard in analytical development.
• Custom Synthesis Building Block: Supplied to fine chemical companies for the contract manufacturing of proprietary compounds and advanced materials.

Basic Information

Product Name	(8Ar)-8A-Methyl-Octahydropyrrolo[1,2-A]Pyrazine Dihydrochloride
CAS No.	2173637-02-8
Molecular Formula	C8H17N3 · 2HCl
Molecular Weight	236.16 g/mol (Free base: 155.24 g/mol)
Synonyms	8a-Methyloctahydropyrrolo[1,2-a]pyrazine dihydrochloride; (8aR)-8a-Methylhexahydro-1H-pyrrolo[1,2-a]pyrazine dihydrochloride; (8aR)-8a-Methyloctahydropyrrolo[1,2-a]pyrazine dihydrochloride; Pyrrolo[1,2-a]pyrazine, octahydro-8a-methyl-, (8aR)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our (8Ar)-8A-Methyl-Octahydropyrrolo[1,2-A]Pyrazine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and cGMP starting material applications. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.