Description

2-Pyrazinemethanol, 6-[(2-Amino-3-Chloro-4-Pyridinyl)Thio]-3-[(3S,4S)-4-Amino-3-Methyl-2-Oxa-8-Azaspiro[4.5]Dec-8-Yl]-5-Methyl- is a sophisticated, high-purity pharmaceutical intermediate designed for advanced synthesis. This compound is critical for research and development in medicinal chemistry, offering a complex molecular scaffold for the creation of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates, particularly in oncology and other targeted therapy areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Oncology Drug Development: Its specific heterocyclic structure makes it a valuable precursor for potential kinase inhibitors and other targeted cancer therapies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical and cellular assays due to its functional groups.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Item	Details
Product Name	2-Pyrazinemethanol, 6-[(2-Amino-3-Chloro-4-Pyridinyl)Thio]-3-[(3S,4S)-4-Amino-3-Methyl-2-Oxa-8-Azaspiro[4.5]Dec-8-Yl]-5-Methyl-
CAS No.	2172652-48-9
Molecular Formula	C20H27ClN6O2S
Molecular Weight	450.99 g/mol
Synonyms	6-[(2-Amino-3-chloro-4-pyridinyl)thio]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]dec-8-yl]-5-methyl-2-pyrazinemethanol; (3S,4S)-8-[6-[(2-Amino-3-chloro-4-pyridinyl)thio]-5-methyl-2-pyrazinyl]-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decane-8-methanol; UNII-7F3K3J1T1F; 2172652-48-9; Spirocyclic Pyrazine Derivative; Chloro-Amino Pyridine Thioether Pyrazinemethanol
EINECS	Contact for details

Quality Control

Our 2-Pyrazinemethanol, 6-[(2-Amino-3-Chloro-4-Pyridinyl)Thio]-3-[(3S,4S)-4-Amino-3-Methyl-2-Oxa-8-Azaspiro[4.5]Dec-8-Yl]-5-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.