Description

α-Amine-ω-Propionic Acid Decaethylene Glycol is a specialized, high-purity polyethylene glycol (PEG) derivative featuring a terminal amine and a propionic acid group. This bifunctional structure is critical for creating stable, water-soluble conjugates and linkages in advanced material science and pharmaceutical applications. It is an essential building block for researchers and manufacturers in the pharmaceutical, bioconjugation, and specialty polymer industries seeking to modify solubility, introduce reactive sites, or create novel drug delivery systems.

Application

• Pharmaceutical Linker & Conjugation: Used as a heterobifunctional crosslinker for attaching peptides, proteins, or drug molecules, leveraging its amine and carboxylic acid termini for selective coupling reactions.
• PEGylation Reagent: Serves as a key intermediate in the synthesis of PEGylated therapeutics to enhance drug solubility, prolong circulation half-life, and reduce immunogenicity.
• Polymer & Material Science: Acts as a functional monomer or macromonomer for synthesizing advanced hydrogels, smart polymers, and surface coatings with tailored properties.
• Diagnostic Reagents: Employed in the development of diagnostic assays and imaging probes where stable, hydrophilic spacers are required between functional components.
• Biomaterial Functionalization: Used to introduce reactive amine or carboxyl groups onto surfaces of nanoparticles, medical devices, or scaffolds to promote further biofunctionalization.
• Cosmetic & Personal Care Ingredients: Functions as a high-performance moisturizing agent and stabilizer in premium skincare formulations due to its excellent humectant properties.

Basic Information

Product Name	α-Amine-ω-Propionic Acid Decaethylene Glycol
CAS No.	2170987-85-4
Molecular Formula	C26H53NO13 (Typical for PEG10 derivative)
Molecular Weight	~587.7 g/mol
Synonyms	α-Amino-ω-propionic acid-PEG10; H2N-PEG10-COOH; Amine-PEG10-Acid; Amino-PEG10-Propionic Acid; Heterobifunctional PEG10 (Amine, Carboxyl); Poly(ethylene glycol) bis(3-aminopropyl) terminated (variant); PEG 500 Monomethyl Ether Amine Propionic Acid (approximate MW)
EINECS	Contact for details

Quality Control

Our α-Amine-ω-Propionic Acid Decaethylene Glycol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for sensitive applications like bioconjugation. We provide comprehensive Certificates of Analysis (COA) that include data for identity, assay, and critical impurities. Specifications are designed to meet the demanding requirements of pharmaceutical research and GMP-grade material production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake. For optimal shelf life, store under an inert atmosphere such as nitrogen or argon after initial opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Amine Value (Titration)	Contact for details
Acid Value (Titration)	Contact for details
Molecular Weight Distribution (GPC)	Polydispersity (PDI) ≤ 1.05
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.