Description

tert-Butyl (S)-4-(4-((Benzyloxy)Carbonyl)-3-(Cyanomethyl)Piperazin-1-Yl)-2-Chloro-5,8-Dihydropyrido[3,4-D]Pyrimidine-7(6H)-Carboxylate is a sophisticated, high-purity chemical intermediate designed for advanced pharmaceutical research and development. This compound is critical for medicinal chemists working on targeted therapies, particularly in oncology and other disease areas involving kinase inhibition. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and complex small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Preclinical Drug Development: Serves as a critical precursor for generating compounds for biological screening and pharmacological evaluation.
• Process Chemistry: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Useful for creating tool compounds to study specific biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.

Basic Information

Product Name	tert-Butyl (S)-4-(4-((Benzyloxy)Carbonyl)-3-(Cyanomethyl)Piperazin-1-Yl)-2-Chloro-5,8-Dihydropyrido[3,4-D]Pyrimidine-7(6H)-Carboxylate
CAS No.	2158302-03-3
Molecular Formula	C30H34ClN5O4
Molecular Weight	572.08 g/mol
Synonyms	(S)-tert-Butyl 4-(4-((benzyloxy)carbonyl)-3-(cyanomethyl)piperazin-1-yl)-2-chloro-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate; UNII-6V6Y1B3W8H; 6V6Y1B3W8H; tert-Butyl (S)-4-(4-((benzyloxy)carbonyl)-3-(cyanomethyl)piperazin-1-yl)-2-chloro-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate; BDBM50389357; AKOS040745615; Z57108255; A1-00818
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), suitable for demanding research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality systems are designed to support GMP-grade development and ensure batch-to-batch consistency for critical R&D projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is light-sensitive and should be handled under inert atmosphere when possible to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.