Description

Methyl-Peg24-Amine CAS NO 2151823-08-2 is a high-purity, monodisperse polyethylene glycol (PEG) derivative featuring a terminal primary amine group. This bifunctional molecule is critical for creating stable, biocompatible conjugates in advanced pharmaceutical and biotech applications. It is primarily used by researchers and manufacturers in drug delivery, bioconjugation, and surface modification who require precise linker chemistry and reliable solubility enhancement.

Application

• Pharmaceutical Conjugation: A key linker for PEGylating peptides, proteins, and oligonucleotides to improve pharmacokinetics, solubility, and stability.
• Drug Delivery Systems: Functionalization of liposomes, nanoparticles, and micelles for targeted delivery and enhanced circulation time.
• Bioconjugation & Cross-linking: Covalent attachment of biomolecules, dyes, or other functional groups to surfaces or other molecules via the reactive amine group.
• Surface Modification: Creating hydrophilic, non-fouling coatings on medical devices, sensors, and diagnostic platforms.
• Hydrogel Formation: Acting as a cross-linking agent in the synthesis of biocompatible hydrogels for tissue engineering and controlled release.
• Diagnostic Reagents: Modification of antibodies or enzymes used in immunoassays and biosensors.

Basic Information

Product Name	Methyl-Peg24-Amine
CAS No.	2151823-08-2
Molecular Formula	C49H101NO24 (Typical for monodisperse PEG24)
Molecular Weight	~1103.4 g/mol (Theoretical)
Synonyms	mPEG24-NH2; α-Methyl-ω-amino-poly(ethylene glycol) (24 EO units); Methoxy-PEG24-amine; 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-Methoxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine; O-Methyl-O'-(2-aminoethyl)hexacosaethylene glycol; PEG Methyl Ether Amine (n=24)
EINECS	Contact for details

Quality Control

Our Methyl-Peg24-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and mass spectrometry for molecular weight verification. We provide comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
PEG Content (NMR)	24 ± 1 EO units
Amine Value (Titration)	0.85 - 1.05 meq/g
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.