Description

(R)-tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate is a high-purity chiral piperazine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, enabling precise control over the final product's biological activity. This compound is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in the research and production of advanced, stereoselective pesticides and herbicides.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in catalytic asymmetric reactions to introduce stereocenters.
• Peptidomimetics Research: Valuable scaffold for designing and synthesizing peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(R)-tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate
CAS No.	2135284-21-6
Molecular Formula	C15H20N2O3
Molecular Weight	276.33 g/mol
Synonyms	1-Boc-3-oxo-2-phenyl-(R)-piperazine; tert-Butyl (3R)-3-oxo-2-phenylpiperazine-1-carboxylate; (R)-1-(tert-Butoxycarbonyl)-3-oxo-2-phenylpiperazine; (R)-Boc-3-oxo-2-phenylpiperazine; (3R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-3-oxo-2-phenylpiperazine; (R)-N-Boc-2-phenylpiperazin-3-one; (R)-2-Phenyl-1,4-diazepan-5-one-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.