Description

3,4-Dihydro-4-[[2-Hydroxy-1-(Hydroxymethyl)Ethoxy] Methyl]-3-Oxo-2-Pyrazinecarboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules and investigational new drugs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• API Synthesis: A key building block for constructing the core scaffold of target APIs, especially in areas like oncology and antiviral research.
• Process Chemistry: Employed in route scouting and optimization for scalable and efficient manufacturing processes.
• Bioconjugation: Potential use in creating drug-linker systems for antibody-drug conjugates (ADCs) due to its functionalizable groups.
• Chemical Biology: Can be utilized as a probe or tool compound for studying biological pathways and target engagement.

Basic Information

Product Name	3,4-Dihydro-4-[[2-Hydroxy-1-(Hydroxymethyl)Ethoxy] Methyl]-3-Oxo-2-Pyrazinecarboxamide
CAS No.	2122281-54-1
Molecular Formula	C10H15N3O6
Molecular Weight	273.25 g/mol
Synonyms	4-[[(2S)-2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3-oxo-3,4-dihydro-2-pyrazinecarboxamide; 2-Pyrazinecarboxamide, 3,4-dihydro-4-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3-oxo-; (S)-4-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)-3-oxo-3,4-dihydropyrazine-2-carboxamide; Advanced Pyrazine Derivative; Pharmaceutical Intermediate 2122281-54-1
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-4-[[2-Hydroxy-1-(Hydroxymethyl)Ethoxy] Methyl]-3-Oxo-2-Pyrazinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP starting material applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation upon exposure to air. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.