Description

tert-Butyl 4-Cyano-2,2-Dimethylpiperidine-1-Carboxylate is a high-value, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its structure, featuring a cyano group and a Boc-protected amine, makes it an essential intermediate for constructing complex molecules with precise stereochemistry and functional group diversity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of piperidine-based active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) and metabolic disorder treatments.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the 2,2-dimethylpiperidine scaffold is required.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and library generation for high-throughput screening.
• Academic Research: A valuable reagent in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	tert-Butyl 4-Cyano-2,2-Dimethylpiperidine-1-Carboxylate
CAS No.	2122117-50-2
Molecular Formula	C13H22N2O2
Molecular Weight	238.33 g/mol
Synonyms	1-Boc-4-cyano-2,2-dimethylpiperidine; 4-Cyano-2,2-dimethylpiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-cyano-2,2-dimethyl-1-piperidinecarboxylate; 2,2-Dimethyl-4-cyanopiperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-cyano-2,2-dimethylpiperidine; Boc-4-CN-2,2-dimethylpiperidine; 4-Cyano-2,2-dimethyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Cyano-2,2-Dimethylpiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.