Description

6-Amino-[1,2,4]triazolo[4,3-a]pyrazine is a high-purity heterocyclic organic compound featuring a fused triazolopyrazine core, serving as a critical advanced pharmaceutical intermediate and versatile chemical building block. Its unique molecular architecture makes it invaluable for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapeutics. This compound is essential for research and manufacturing in pharmaceutical, agrochemical, and specialty fine chemical sectors, where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in oncology and antiviral therapeutic areas.
• Kinase Inhibitor Synthesis: Core building block for constructing potent and selective kinase inhibitors used in targeted cancer therapies.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides with specific modes of action.
• Material Science: Potential precursor for the synthesis of nitrogen-rich heterocyclic compounds used in advanced materials and ligands for catalysis.
• Chemical Biology & Proteomics: Useful as a tagged molecular probe or scaffold for studying protein-ligand interactions and enzyme activity.
• Academic & Contract Research: Serves as a valuable reagent for methodological studies in organic synthesis and medicinal chemistry within R&D laboratories.

Basic Information

Product Name	6-Amino-[1,2,4]triazolo[4,3-a]pyrazine
CAS No.	2111465-25-7
Molecular Formula	C5H4N6
Molecular Weight	148.13 g/mol
Synonyms	6-Amino-[1,2,4]triazolopyrazine; [1,2,4]Triazolo[4,3-a]pyrazin-6-amine; 6-Amino-1,2,4-triazolo[4,3-a]pyrazine; 6-Amino-s-triazolo[4,3-a]pyrazine; 6-ATZP; 6-Amino-1H-[1,2,4]triazolo[4,3-a]pyrazine; 6-Amino-1,2,4-triazolopyrazine; 6-Amino-1,2,4-triazolo[4,3-a]pyrazine (CAS 2111465-25-7)
EINECS	Contact for details

Quality Control

Our 6-Amino-[1,2,4]triazolo[4,3-a]pyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP manufacturing. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF for moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.