Description

Cyclohexanamine, 4-(1-Piperidinyl)-, Hydrochloride (1:2), trans- is a high-purity, specialized organic salt with the CAS number 2108723-89-1. This compound is valued for its defined stereochemistry and serves as a critical building block in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, particularly for the development of novel therapeutic agents and as a key chiral intermediate.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and other therapeutic targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor for constructing complex molecular libraries in drug discovery programs.
• Chemical Synthesis: Serves as a versatile building block for the preparation of more complex amines, ligands, and specialty chemicals.
• Catalyst and Ligand Development: Potential use in the synthesis of chiral ligands for asymmetric catalysis.
• Academic and Industrial R&D: Employed in research laboratories for studying structure-activity relationships (SAR) and novel synthetic pathways.

Basic Information

Product Name	Cyclohexanamine, 4-(1-Piperidinyl)-, Hydrochloride (1:2), trans-
CAS No.	2108723-89-1
Molecular Formula	C11H22N2 • 2HCl
Molecular Weight	263.23 g/mol (Free base: 182.31 g/mol)
Synonyms	trans-4-(Piperidin-1-yl)cyclohexanamine dihydrochloride; 4-Piperidin-1-yl-cyclohexylamine dihydrochloride, trans-; (1r,4r)-4-(Piperidin-1-yl)cyclohexan-1-amine dihydrochloride; (trans)-4-(1-Piperidinyl)cyclohexanamine dihydrochloride; 4-(Piperidin-1-yl)cyclohexanamine hydrochloride (2:1); trans-4-Aminocyclohexylpiperidine dihydrochloride; 4-(1-Piperazinyl)cyclohexanamine dihydrochloride (common mis-assignment); UNII- Contact for details
EINECS	Contact for details

Quality Control

Our Cyclohexanamine, 4-(1-Piperidinyl)-, Hydrochloride (1:2), trans- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Trans Isomer Content (Chiral HPLC)	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.