Description

tert-Butyl 4-Hydrazinylpiperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive hydrazinyl group, which enables the construction of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Chemical Biology & Proteomics: Serves as a versatile linker or reagent for bioconjugation and probe development.
• Heterocyclic Chemistry: Enables the synthesis of complex piperidine- and hydrazine-containing heterocycles for material science applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	tert-Butyl 4-Hydrazinylpiperidine-1-Carboxylate
CAS No.	2108550-78-1
Molecular Formula	C10H21N3O2
Molecular Weight	215.29 g/mol
Synonyms	1-Boc-4-hydrazinylpiperidine; 4-Hydrazinyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-hydrazinopiperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-hydrazinylpiperidine; 4-Hydrazinylpiperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-hydrazinopiperidine; Boc-4-hydrazinopiperidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-Hydrazinylpiperidine-1-Carboxylate adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.