Description

1-Piperazinecarboxylic Acid, 4-[(2-Amino-4-Pyridinyl)Methyl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-pyridine hybrid structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel, small-molecule therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for targeting central nervous system (CNS) disorders and other complex diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Drug Discovery Research: Used as a versatile scaffold in medicinal chemistry for creating compound libraries and optimizing lead molecules.
• CNS-Targeted Therapies: Employed in the development of potential treatments for neurological and psychiatric conditions due to its ability to modulate relevant biological pathways.
• Kinase Inhibitor Development: Serves as a core structural component in the design of novel kinase inhibitors for oncology and inflammatory disease research.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for cGMP-scale production of clinical trial materials.
• Academic & Biotech R&D: Utilized in university and biotechnology company laboratories for basic research and proof-of-concept studies.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-[(2-Amino-4-Pyridinyl)Methyl]-, 1,1-Dimethylethyl Ester
CAS No.	2101928-45-2
Molecular Formula	C15H24N4O2
Molecular Weight	292.38 g/mol
Synonyms	tert-Butyl 4-[(2-amino-4-pyridinyl)methyl]-1-piperazinecarboxylate; 4-[(2-Amino-4-pyridinyl)methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 2-Amino-4-(4-Boc-piperazin-1-ylmethyl)pyridine; Boc-4-[(2-amino-4-pyridyl)methyl]piperazine; N-Boc-4-((2-amino-4-pyridyl)methyl)piperazine; 1,1-Dimethylethyl 4-[(2-amino-4-pyridinyl)methyl]-1-piperazinecarboxylate
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 4-[(2-Amino-4-Pyridinyl)Methyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical research and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.