Description

(7R,8As)-Octahydropyrrolo[1,2-A]Piperazin-7-O Oxalic Acid CAS NO 2101775-04-4 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drugs, including potential candidates for neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Neurological Drug Research: Used in the R&D of potential therapeutics targeting specific receptors in the central nervous system.
• Metabolic Disorder Therapeutics: Serves as a precursor in the development of compounds for metabolic disease pathways.
• Asymmetric Synthesis: Leveraged in stereoselective chemical reactions to create enantiomerically pure compounds.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial production.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	(7R,8As)-Octahydropyrrolo[1,2-A]Piperazin-7-O Oxalic Acid
CAS No.	2101775-04-4
Molecular Formula	C10H16N2O5
Molecular Weight	244.25 g/mol
Synonyms	(7R,8as)-Octahydro-2H-pyrrolo[1,2-a]pyrazin-7-ol oxalate; (7R,8as)-Octahydropyrrolo[1,2-a]pyrazin-7-ol ethanedioate; 7R,8aS-Octahydro-2H-pyrrolo[1,2-a]pyrazin-7-ol oxalic acid salt; (7R,8aS)-Octahydro-2H-pyrrolo[1,2-a]pyrazin-7-ol oxalate; Pyrrolopiperazine oxalate derivative; (7R,8aS)-Octahydropyrrolopyrazin-7-ol oxalate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is controlled to meet strict specifications for identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing results from analytical methods such as HPLC, chiral chromatography, and NMR. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.