Description

Hexanoic Acid, 3-(Chloromethyl)-, (3R)- is a chiral, functionalized fatty acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a chloromethyl group on a stereodefined carbon backbone, makes it a versatile intermediate for constructing complex molecules with high enantiomeric purity. This compound is particularly valuable for researchers and process chemists in the pharmaceutical and agrochemical industries developing new active ingredients, where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where the specific (R)-configuration can influence biological activity and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands, auxiliaries, and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Polymer Modification: Can be used to introduce chiral centers or reactive handles into polymer chains for advanced material science applications.
• Academic and R&D: A valuable tool for methodological development in organic chemistry and for studying structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	Hexanoic Acid, 3-(Chloromethyl)-, (3R)-
CAS No.	2101641-90-9
Molecular Formula	C7H13ClO2
Molecular Weight	164.63 g/mol
Synonyms	(R)-3-(Chloromethyl)hexanoic acid; (3R)-3-(Chloromethyl)hexanoic acid; (R)-3-(Chloromethyl)caproic acid; D-3-(Chloromethyl)hexanoic acid; (+)-3-(Chloromethyl)hexanoic acid; (R)-Hexanoic acid, 3-(chloromethyl)-; 3-(Chloromethyl)hexanoic acid (R)-enantiomer
EINECS	Contact for details

Quality Control

We supply Hexanoic Acid, 3-(Chloromethyl)-, (3R)- in high-purity grades suitable for demanding synthetic applications. Our products undergo rigorous quality testing, including chiral purity analysis (HPLC/Chiral GC), to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess (ee), and impurity profile is provided with each batch. Custom synthesis and purification to meet specific project requirements, including cGMP standards for pharmaceutical development, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.