Description

tert-Butyl cis-3-Amino-5-Methoxypiperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile, stereochemically defined scaffold for constructing complex molecules, enabling precise control over the final product's biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for efficacy.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, activity-based probes (ABPs), and other research tools.
• Peptidomimetics & Drug Discovery: The protected amino and methoxy groups make it a valuable scaffold for creating peptide mimics and small molecule libraries.
• Catalyst & Ligand Development: Utilized as a starting material for synthesizing novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Contract Research: A fundamental reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	tert-Butyl cis-3-Amino-5-Methoxypiperidine-1-Carboxylate
CAS No.	2101218-75-9
Molecular Formula	C12H24N2O3
Molecular Weight	244.33 g/mol
Synonyms	1-Boc-3-amino-5-methoxypiperidine (cis); cis-1-(tert-Butoxycarbonyl)-3-amino-5-methoxypiperidine; tert-Butyl 3-amino-5-methoxypiperidine-1-carboxylate (cis); 3-Amino-5-methoxy-1-piperidinecarboxylic acid 1,1-dimethylethyl ester (cis); (3R,5S)-tert-Butyl 3-amino-5-methoxypiperidine-1-carboxylate; (3S,5R)-tert-Butyl 3-amino-5-methoxypiperidine-1-carboxylate; BOC-3-Amino-5-Methoxypiperidine (cis); cis-3-Amino-5-methoxy-N-Boc-piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl cis-3-Amino-5-Methoxypiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, confirming compliance with customer requirements and internal standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (cis isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.