Description

Benzyloxy Carbonyl-Peg3-Acid CAS NO 2100306-73-6 is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring a benzyloxycarbonyl (Cbz) protecting group and a carboxylic acid terminus. This compound is essential for creating stable, hydrophilic spacers in bioconjugation and pharmaceutical development, enabling precise control over molecular architecture. It is primarily utilized by researchers and manufacturers in the fields of proteomics, antibody-drug conjugate (ADC) development, and peptide synthesis.

Application

• Bioconjugation Linker: Serves as a critical spacer for attaching drugs, dyes, or other functional molecules to proteins, peptides, or antibodies, particularly in ADC development.
• Peptide Synthesis: Used as a building block or protecting group strategy in solid-phase and solution-phase peptide chemistry.
• Polymer Chemistry: Acts as a functional initiator or monomer for synthesizing tailored PEG-based polymers and hydrogels with specific end-group functionality.
• Drug Delivery Systems: Incorporated into nanocarriers and prodrugs to enhance solubility, prolong circulation time, and improve pharmacokinetic profiles.
• Diagnostic Reagents: Facilitates the labeling of biomolecules with contrast agents or fluorescent probes for imaging and diagnostic assays.
• Surface Modification: Used to functionalize materials and nanoparticles with carboxylic acid groups for subsequent coupling reactions.

Basic Information

Product Name	Benzyloxy Carbonyl-Peg3-Acid
CAS No.	2100306-73-6
Molecular Formula	C19H28O8
Molecular Weight	384.42 g/mol
Synonyms	Z-PEG3-acid; Cbz-PEG3-COOH; Benzyl N-(2-{2-[2-(Carboxymethoxy)ethoxy]ethoxy}ethyl)carbamate; Carbobenzoxy-PEG3-acid; N-Carbobenzyloxy-3,6,9-trioxaundecanedioic acid 11-methyl ester; 3,6,9-Trioxaundecanedioic acid, 11-[[(phenylmethoxy)carbonyl]amino]-, 1-methyl ester; (2-{2-[2-({[(Benzyloxy)carbonyl]amino}ethoxy)ethoxy]ethoxy)acetic acid
EINECS	Contact for details

Quality Control

Our Benzyloxy Carbonyl-Peg3-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.