Description

2-Piperazinone, 1-(2,2,2-Trifluoroethyl)-, Hydrochloride (1:1) is a high-purity, specialized organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical building block for the development of novel pharmaceutical candidates and agrochemicals, offering a unique trifluoroethyl-substituted piperazinone scaffold. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: A versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Agrochemical Development: Used in the research and synthesis of novel herbicides and pesticides, leveraging the biological activity of the piperazinone core.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes used in biochemical and cellular assays.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	2-Piperazinone, 1-(2,2,2-Trifluoroethyl)-, Hydrochloride (1:1)
CAS No.	2098114-26-0
Molecular Formula	C6H10F3N2O • HCl
Molecular Weight	220.61 g/mol (Free base: 184.15 g/mol)
Synonyms	1-(2,2,2-Trifluoroethyl)piperazin-2-one hydrochloride; 1-(Trifluoroethyl)-2-piperazinone hydrochloride; 2-Piperazinone, 1-(2,2,2-trifluoroethyl)-, monohydrochloride; 2098114-26-0; 1-(2,2,2-Trifluoroethyl)piperazin-2-one HCl; Trifluoroethyl piperazinone hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Piperazinone, 1-(2,2,2-Trifluoroethyl)-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.