Description

Hoocch2Ch2O-Peg10-Ch2Ch2Cooh is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative, also known as a dicarboxyl-functionalized PEG10 spacer. This compound is engineered to serve as a versatile linker or cross-linking agent, providing controlled spacing and aqueous solubility in advanced formulations. It is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors who require precise molecular architecture for drug delivery systems, hydrogel formation, and surface functionalization. Its defined structure ensures reproducible performance in sensitive applications.

Application

• Bioconjugation & Drug Delivery: A key linker for attaching therapeutic agents (e.g., peptides, proteins, small molecules) to carriers like antibodies or nanoparticles, creating stable, soluble PEGylated constructs.
• Hydrogel & Biomaterial Synthesis: Acts as a cross-linker for creating biocompatible hydrogels with tunable mechanical properties for tissue engineering, wound dressings, and 3D cell culture scaffolds.
• Surface Functionalization: Used to modify surfaces (e.g., gold nanoparticles, silica, medical devices) with carboxyl groups for subsequent covalent attachment of biomolecules or to create non-fouling coatings.
• Diagnostic Reagents: Employed in the development of diagnostic assays and imaging probes, where it links targeting moieties to signal-generating molecules while improving solubility and stability.
• Polymer Chemistry: Serves as a macroinitiator or building block for synthesizing advanced block copolymers and functionalized polymers with specific end-group reactivity.
• ADC (Antibody-Drug Conjugate) Development: Provides a PEG spacer arm in ADC linker-payload systems to optimize pharmacokinetics and reduce aggregation.

Basic Information

Product Name	Hoocch2Ch2O-Peg10-Ch2Ch2Cooh
CAS No.	2097010-30-3
Molecular Formula	C28H54O15
Molecular Weight	630.7 g/mol
Synonyms	α,ω-Dicarboxy PEG10; 3,6,9,12,15,18,21,24,27,30-Decaoxadotetracontanedioic acid; PEG-10 dicarboxylic acid; HOOC-PEG10-COOH; Dicarboxy-functionalized PEG (n=10); 15-Carboxy-4,7,10,13-tetraoxapentadecanoic acid, extended; Poly(ethylene glycol) bis(carboxymethyl) ether (n~10); Carboxy-PEG10-acid
EINECS	Contact for details

Quality Control

Our Hoocch2Ch2O-Peg10-Ch2Ch2Cooh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistent molecular weight distribution, and functional group integrity. Standard quality checks include NMR, HPLC, and titration for carboxyl group quantification. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP-oriented research and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Molecular Weight (SEC/GPC)	600 - 660 g/mol
Acid Value (Titration)	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.