Description

Gsk269962 Hydrochloride is a potent and selective small molecule inhibitor of ROCK (Rho-associated coiled-coil containing protein kinase) activity. This compound is a critical research tool for investigating cellular signaling pathways related to cytoskeletal dynamics, cell motility, and vascular function. It is primarily utilized by pharmaceutical R&D teams and academic researchers in the fields of oncology, cardiovascular disease, and neurobiology. The product, identified by CAS NO 2095432-71-4, is supplied under stringent quality control to ensure reliable and reproducible experimental results.

Application

• Biomedical Research: A key reagent for studying the role of ROCK kinases in cell contraction, adhesion, and migration.
• Drug Discovery & Development: Used as a reference standard and pharmacological probe in high-throughput screening and target validation studies for cancer and fibrotic diseases.
• Cardiovascular Research: Investigates pathways involved in hypertension, atherosclerosis, and pulmonary arterial hypertension by modulating vascular smooth muscle cell tone.
• Neuroscience Studies: Explores mechanisms of axonal growth, regeneration, and the pathophysiology of neurological disorders like stroke and Alzheimer's disease.
• In Vitro & In Vivo Models: Applied in cellular assays and animal models to elucidate disease mechanisms and evaluate therapeutic potential.

Basic Information

Product Name	Gsk269962 Hydrochloride
CAS No.	2095432-71-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GSK269962 HCl; GSK-269962 hydrochloride; (R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide, 2HCl; ROCK Inhibitor GSK269962; Rho Kinase Inhibitor GSK269962
EINECS	Contact for details

Quality Control

Our Gsk269962 Hydrochloride is manufactured and tested under a quality management system to ensure high purity and batch-to-batch consistency for research applications. Each lot undergoes rigorous analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.