Description

1-(1-Methylazetidin-3-Yl)Piperazine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small molecule therapeutics targeting central nervous system and other disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting GPCRs and other neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Bioconjugation & Probe Development: The piperazine moiety can be utilized for the development of chemical probes, imaging agents, or antibody-drug conjugates (ADCs).
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Item	Details
Product Name	1-(1-Methylazetidin-3-Yl)Piperazine Dihydrochloride
CAS No.	2095410-68-5
Molecular Formula	C8H20Cl2N4
Molecular Weight	243.18 g/mol
Synonyms	1-(1-Methylazetidin-3-yl)piperazine dihydrochloride; 1-(1-Methyl-3-azetidinyl)piperazine dihydrochloride; 1-Methyl-3-(piperazin-1-yl)azetidine dihydrochloride; 1-(1-Methylazetidin-3-yl)piperazine hydrochloride (1:2); 2095410-68-5; 1-Methyl-3-piperazin-1-yl-azetidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(1-Methylazetidin-3-Yl)Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.