Description

Ethyl 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carboxylate, Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its value lies in its role as a key precursor for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system. This compound is essential for research and development chemists, process development scientists, and manufacturers within the global pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug candidates, especially those with pyrazolo-pyrazine core structures.
• Neurological Drug Research: Serves as a key precursor for the development of potential therapeutics targeting neurological disorders and psychiatric conditions.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, scalable synthetic routes for commercial API manufacturing under GMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies in drug discovery and development pipelines.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and novel synthetic methodology development.

Basic Information

Product Name	Ethyl 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carboxylate, Hydrochloride
CAS No.	2070015-34-6
Molecular Formula	C11H16ClN3O2
Molecular Weight	257.72 g/mol
Synonyms	Ethyl 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate hydrochloride; 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester hydrochloride; Pyrazolo[1,5-a]pyrazine-2-carboxylic acid, 4,5,6,7-tetrahydro-, ethyl ester, hydrochloride; CAS 2070015-34-6; Ethyl 4,5,6,7-tetrahydro-2H-pyrazolo[1,5-a]pyrazine-2-carboxylate HCl; 2-Carbethoxy-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carboxylate, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment. We support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent exposure to atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.