Description

3-Bromo-4H,5H,6H,7H-Pyrazolo[1,5-A]Pyrazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrazine chemical class. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Synthesis: Serves as a core structural component in the synthesis of potential kinase inhibitors for oncology targets.
• CNS Drug Development: Employed in the construction of heterocyclic compounds being investigated for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to create specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	3-Bromo-4H,5H,6H,7H-Pyrazolo[1,5-A]Pyrazine Hydrochloride
CAS No.	2059994-83-9
Molecular Formula	C7H9BrClN3
Molecular Weight	250.52 g/mol
Synonyms	3-Bromopyrazolo[1,5-a]pyrazine hydrochloride; 3-Bromo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine hydrochloride; 3-Bromo-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a]pyrazine hydrochloride; Pyrazolo[1,5-a]pyrazine, 3-bromo-4,5,6,7-tetrahydro-, hydrochloride; 2059994-83-9; 3-Bromo-1,4,5,6,7,8-hexahydropyrazolo[1,5-a]pyrazine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-4H,5H,6H,7H-Pyrazolo[1,5-A]Pyrazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All batches undergo comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.