Description

(R)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One Hydrochloride is a high-purity chiral piperazinone derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. This compound is essential for research and development organizations and pharmaceutical manufacturers focused on creating novel therapeutics, including potential candidates for central nervous system (CNS) and other targeted disease treatments.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in drug discovery programs.
• Asymmetric Synthesis: Employed in the development of stereoselective synthetic routes due to its defined (R)-configuration.
• Process Chemistry Development: Serves as a critical intermediate for scaling up the synthesis of candidate drugs from laboratory to pilot plant scale.
• Biochemical Research: Potential use as a tool compound for studying enzyme inhibition or receptor-ligand interactions.
• Contract Manufacturing (CMO/CDMO): Supplied to organizations specializing in the custom synthesis of complex organic molecules for clinical trials.

Basic Information

Product Name	(R)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One Hydrochloride
CAS No.	2055848-90-1
Molecular Formula	C15H23ClN2O3
Molecular Weight	314.81 g/mol
Synonyms	(R)-4-(2,4-Dimethoxybenzyl)-3-methyl-2-oxopiperazine hydrochloride; (R)-3-Methyl-4-(2,4-dimethoxybenzyl)piperazin-2-one hydrochloride; 4-[(2,4-Dimethoxyphenyl)methyl]-3-methyl-2-piperazinone hydrochloride, (3R)-; (R)-3-Methyl-4-(2,4-dimethoxybenzyl)-3,4-dihydro-2(1H)-pyrazinone hydrochloride; (R)-4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one HCl; 2055848-90-1; (R)-enantiomer of 4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere if opened frequently to prevent degradation from moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.