Description

(S)-2-Phenethylpiperazine Dihydrochloride is a high-purity chiral piperazine derivative, specifically the (S)-enantiomer, supplied as a stable dihydrochloride salt. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries and exploring structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up of enantiomerically pure APIs requiring the (S)-2-phenethylpiperazine moiety.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.

Basic Information

Product Name	(S)-2-Phenethylpiperazine Dihydrochloride
CAS No.	2055848-89-8
Molecular Formula	C₁₂H₂₀Cl₂N₂
Molecular Weight	263.20 g/mol
Synonyms	(S)-1-(2-Phenylethyl)piperazine Dihydrochloride; (S)-2-(2-Phenylethyl)piperazine Dihydrochloride; (S)-1-Phenethylpiperazine Dihydrochloride; (S)-N-Phenethylpiperazine Dihydrochloride; (S)-Phenethylpiperazine Dihydrochloride; (S)-PEP Dihydrochloride; (S)-2-PEP.2HCl
EINECS	Contact for details

Quality Control

Our (S)-2-Phenethylpiperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.