Description

3-((3-Amino-2-Chlorophenyl)Thio)-6-Chloropyrazin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrazine-thiophene core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides, leveraging its heterocyclic structure.
• Material Science: Used in the research and development of organic electronic materials and specialty polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for the custom manufacturing of complex, multi-functional organic molecules.

Basic Information

Product Name	3-((3-Amino-2-Chlorophenyl)Thio)-6-Chloropyrazin-2-Amine
CAS No.	2055841-11-5
Molecular Formula	C10H8Cl2N4S
Molecular Weight	287.16 g/mol
Synonyms	6-Chloro-3-[(3-amino-2-chlorophenyl)thio]pyrazin-2-amine; 3-((3-Amino-2-chlorophenyl)thio)-6-chloro-2-pyrazinamine; 2-Amino-3-((3-amino-2-chlorophenyl)thio)-6-chloropyrazine; 2055841-11-5; 6-Chloro-3-[(3-amino-2-chlorophenyl)sulfanyl]pyrazin-2-amine
EINECS	Contact for details

Quality Control

Our 3-((3-Amino-2-Chlorophenyl)Thio)-6-Chloropyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.