Description

n-(Boc-Peg3)-n-Bis-(Peg2-Alcohol) CAS NO 2055042-60-7 is a specialized heterobifunctional polyethylene glycol (PEG) derivative featuring a tert-butyloxycarbonyl (Boc) protected amine at one terminus and dual alcohol functionalities at the other. This compound matters as a versatile, high-purity linker and spacer molecule, enabling controlled conjugation and solubility enhancement in advanced chemical synthesis. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries for developing prodrugs, polymer therapeutics, and functionalized biomaterials.

Application

• Pharmaceutical Linker: Used as a cleavable spacer in antibody-drug conjugates (ADCs) and targeted drug delivery systems.
• Prodrug Synthesis: Facilitates the attachment of therapeutic agents via its Boc-protected amine, allowing for controlled release.
• Polymer Modification: Serves as a functional initiator or cross-linker for creating PEG-based hydrogels and smart materials.
• Bioconjugation: Enables the site-specific attachment of peptides, proteins, or labels using its orthogonal amine and alcohol groups.
• Solubility Enhancer: Incorporated into small molecule drugs to improve their aqueous solubility and pharmacokinetic profiles.
• Diagnostic Reagent Intermediate: Used in the synthesis of contrast agents and molecular imaging probes.

Basic Information

Product Name	n-(Boc-Peg3)-n-Bis-(Peg2-Alcohol)
CAS No.	2055042-60-7
Molecular Formula	C24H47NO11
Molecular Weight	525.64 g/mol
Synonyms	1,1'-(2-(2-(2-(2-(2-(3-(Boc-amino)propoxy)ethoxy)ethoxy)ethoxy)ethylazanediyl)bis(ethane-2,1-diyl) diacetate; 2,2'-((2-(2-(2-(2-(2-(3-((tert-Butoxycarbonyl)amino)propoxy)ethoxy)ethoxy)ethoxy)ethyl)azanediyl)bis(ethane-2,1-diyl)) diacetate; Boc-NH-PEG3-N(Bis-PEG2-OH); tert-Butyl (3-(2-(2-(2-(2-(2-(bis(2-(2-hydroxyethoxy)ethyl)amino)ethoxy)ethoxy)ethoxy)ethoxy)propyl)carbamate; Boc-Amine-PEG3-Bis(PEG2-Acetate); Heterobifunctional PEG Boc-amine and diol.
EINECS	Contact for details

Quality Control

Our n-(Boc-Peg3)-n-Bis-(Peg2-Alcohol) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Molecular Weight Confirmation (MS)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.