Description

α,ω-Dipropionic Acid Nonaethylene Glycol is a high-purity, functionalized polyethylene glycol (PEG) derivative, also known as a PEG diacid. This compound is a crucial bifunctional linker and building block in advanced material synthesis, offering reactive carboxylic acid groups at both termini of a hydrophilic PEG spacer. Its primary value lies in enabling the controlled conjugation, cross-linking, and surface modification of biomolecules and polymers. This makes it essential for researchers and manufacturers in the pharmaceutical, biomedical, and specialty polymer industries who require precise, water-soluble spacers for drug delivery systems, hydrogel formation, and bioconjugation.

Application

• Bioconjugation and Drug Delivery: As a heterobifunctional cross-linker for attaching peptides, proteins, or drugs to nanoparticles, surfaces, or other polymers to create PEGylated therapeutics with enhanced solubility and circulation time.
• Hydrogel Synthesis: Serves as a water-soluble macromonomer or cross-linking agent for creating biodegradable and biocompatible hydrogels used in tissue engineering and controlled release applications.
• Polymer Modification: Used to introduce carboxylic acid functionality and hydrophilicity into polymer backbones, modifying properties like solubility, biocompatibility, and reactivity for specialty coatings and adhesives.
• Surface Functionalization: Enables the covalent attachment of bioactive molecules to metal oxide or polymer surfaces (e.g., biosensors, diagnostic chips) via its acid groups, creating non-fouling, bioactive interfaces.
• Intermediate for Specialty Surfactants: Acts as a precursor for synthesizing novel, cleavable surfactants or emulsifiers with specific degradation profiles.
• Research & Development: A key reagent in R&D for exploring new biomaterials, nano-carriers, and responsive polymer systems.

Basic Information

Item	Detail
Product Name	α,ω-Dipropionic Acid Nonaethylene Glycol
CAS No.	2055023-26-0
Molecular Formula	C24H46O14
Molecular Weight	558.62 g/mol
Synonyms	9,12-Dioxa-3,6-dioxo-4,7,10,13-tetraoxahexadecanedioic acid; PEG 400 Diacid; Polyethylene glycol 400 di(propionic acid); Nonaethylene glycol dipropionate; α,ω-Bis(carboxyethyl) nonaethylene glycol; HOOC-CH2CH2-CO-(O-CH2CH2)9-O-CO-CH2CH2-COOH; 3,6,9,12,15,18,21,24,27-Nonaoxahentriacontanedioic acid
EINECS	Contact for details

Quality Control

Our α,ω-Dipropionic Acid Nonaethylene Glycol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data for critical parameters such as assay, acid value, and impurity profiles. Our quality commitment supports applications requiring high reproducibility and traceability, essential for pharmaceutical R&D and GMP-grade material production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 15-25°C. This product is hygroscopic (moisture-sensitive). To prevent degradation and clumping, keep the container tightly sealed when not in use and consider handling under a dry atmosphere for critical applications.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Acid Value	Theoretical range: 195-210 mg KOH/g
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.