Description

Tri(Amino-Peg5-Amide)-Amine Tfa Salt is a high-purity, multi-functional PEG-based amine derivative, essential for advanced bioconjugation and linker chemistry. Its trifluoroacetate (TFA) salt form enhances stability and solubility, making it a critical reagent for precise molecular assembly. This compound is primarily utilized by researchers and manufacturers in pharmaceutical development, proteomics, and the synthesis of next-generation antibody-drug conjugates (ADCs) and diagnostic agents.

Application

• Bioconjugation Linker: A key building block for creating stable, cleavable, or non-cleavable linkers in ADC (Antibody-Drug Conjugate) development.
• Proteomics Research: Used in the modification and cross-linking of peptides and proteins for mass spectrometry analysis and structural studies.
• Polymer & Dendrimer Synthesis: Serves as a multi-arm core or branching unit for synthesizing functionalized PEGylated polymers and dendrimers.
• Surface Functionalization: Enables the amine-terminated modification of nanoparticles, biosensors, and other material surfaces for biomedical applications.
• Diagnostic Reagent Precursor: Employed in the production of contrast agents and fluorescent probes for imaging and diagnostic kits.
• Solid-Phase Peptide Synthesis (SPPS): Acts as a soluble, protected amine component for complex peptide assembly.

Basic Information

Product Name	Tri(Amino-Peg5-Amide)-Amine Tfa Salt
CAS No.	2055013-52-8
Molecular Formula	C45H87F3N10O19
Molecular Weight	1129.22 g/mol
Synonyms	N1,N1-Bis[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]glycinamide TFA salt; Tris[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]amine TFA salt; PEG5 Triamine TFA Salt; Amino-PEG5-Tris Amide TFA Salt; 3-Arm PEG5 Amine TFA Salt; Triamino(pentaethylene glycol)amide TFA Salt; 1,1',1''-Nitrilotris[2-oxo-2-(2,5,8,11,14-pentaoxahexadecan-16-ylamino)ethane] TFA salt
EINECS	Contact for details

Quality Control

Our Tri(Amino-Peg5-Amide)-Amine Tfa Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with research and cGMP-grade material standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.