Description

n-Boc-n-Bis(Peg2-Acid) CAS NO 2054339-01-2 is a specialized bifunctional polyethylene glycol (PEG) derivative featuring a tert-butyloxycarbonyl (Boc) protecting group and two carboxylic acid termini. This compound is engineered to serve as a versatile heterobifunctional linker, enabling the controlled conjugation of biomolecules, polymers, or surfaces in advanced research and development. It is a critical reagent for scientists and engineers in the pharmaceutical, bioconjugation, and advanced materials sectors who require precise and stable crosslinking capabilities.

Application

• As a key heterobifunctional crosslinker in the synthesis of antibody-drug conjugates (ADCs) and other bioconjugates.
• For the PEGylation of peptides, proteins, and oligonucleotides to enhance solubility, stability, and pharmacokinetic properties.
• In the development of functionalized hydrogels and biomaterials for drug delivery and tissue engineering applications.
• As a building block for creating dendrimers and complex polymer architectures with tailored properties.
• For the surface modification and functionalization of nanoparticles and diagnostic agents.
• In proteomics research for the site-specific labeling and immobilization of biomolecules.

Basic Information

Product Name	n-Boc-n-Bis(Peg2-Acid)
CAS No.	2054339-01-2
Molecular Formula	C19H34N2O10
Molecular Weight	450.48 g/mol
Synonyms	1,1'-(2,2'-(2-(tert-Butoxycarbonyl)amino)ethylazanediyl)bis(ethane-2,1-diyl))diacetic acid; Boc-NH-PEG2-CH2CH2-COOH; tert-Butyl (2,2'-(2-(2-carboxyethoxy)ethylazanediyl)bis(ethane-2,1-diyl))dicarbamate; N-Boc-N-bis(PEG2-acid); Boc-PEG2-acid linker; Heterobifunctional PEG acid, Boc-protected; 2054339-01-2; Boc-N-amido-PEG2-acid
EINECS	Contact for details

Quality Control

Our n-Boc-n-Bis(Peg2-Acid) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for critical research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.