Description

Azelaprag is a high-purity, non-peptidic GLP-1 receptor agonist developed for pharmaceutical research and development. This compound is significant for its potential in the treatment of metabolic disorders, offering a promising scaffold for novel therapeutics. It is primarily needed by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in the discovery of next-generation treatments for type 2 diabetes and obesity.

Application

• Pharmaceutical R&D: Serves as a key active pharmaceutical ingredient (API) intermediate or reference standard in the development of GLP-1 receptor-targeting drugs.
• Metabolic Disease Research: Used in preclinical studies to investigate mechanisms of action, efficacy, and safety profiles for conditions like type 2 diabetes.
• Biochemical Assay Development: Employed as a tool compound in high-throughput screening (HTS) and binding assays to identify and characterize new drug candidates.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental research on incretin hormone pathways.
• Formulation Studies: Acts as a model compound for developing stable and bioavailable dosage forms, such as oral tablets or injectable solutions.

Basic Information

Product Name	Azelaprag
CAS No.	2049980-18-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PF-07081532; (S)-2-(4-(4-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-isopropyl-1H-indazol-5-yl)piperazin-1-yl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)propan-1-amine; GLP-1 Receptor Agonist (Non-peptidic); PF07081532
EINECS	Contact for details

Quality Control

Our Azelaprag is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.