Description

3-Bromo-6-Ethyl-5-((Tetrahydro-2H-Pyran-4-Yl)Amino)Pyrazine-2-Carbonitrile is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is valued for its unique heterocyclic structure, which serves as a critical building block for synthesizing novel bioactive molecules. It is primarily targeted at medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries working on new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential kinase inhibitors due to its pyrazine-carbonitrile moiety.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological processes and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for clinical trial materials.
• Agrochemical Research: Potential intermediate for developing new agrochemicals, such as herbicides or fungicides, leveraging its heterocyclic framework.

Basic Information

Product Name	3-Bromo-6-Ethyl-5-((Tetrahydro-2H-Pyran-4-Yl)Amino)Pyrazine-2-Carbonitrile
CAS No.	2043019-98-1
Molecular Formula	C12H15BrN4O
Molecular Weight	311.18 g/mol
Synonyms	3-Bromo-6-ethyl-5-[(oxan-4-yl)amino]pyrazine-2-carbonitrile; 5-((Tetrahydro-2H-pyran-4-yl)amino)-3-bromo-6-ethylpyrazine-2-carbonitrile; 3-Bromo-6-ethyl-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carbonitrile; THP-Amino Pyrazine Carbonitrile Bromo Derivative; CAS 2043019-98-1
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Ethyl-5-((Tetrahydro-2H-Pyran-4-Yl)Amino)Pyrazine-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.